Viral infectivity factor photograph

Viral Infectivity Factor

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Classification Protein
Date of Reg.
Date of Upd.
ID2479534
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About Viral Infectivity Factor


Viral infectivity factor, or Vif, is an accessory protein found in HIV and other retroviruses. Its role is to disrupt the antiviral activity of the human enzyme APOBEC by targeting it for ubiquitination and cellular degradation. APOBEC is a cytidine deaminase enzyme that mutates viral nucleic acids.

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