The Bug
| Use attributes for filter ! | |
| Google books | books.google.com |
|---|---|
| Originally published | 2003 |
| Authors | Ellen Ullman |
| Genres | Thriller |
| Suspense | |
| Psychological Fiction | |
| Date of Reg. | |
| Date of Upd. | |
| ID | 2380105 |
About The Bug
"The story is narrated by Roberta Walton from the perspective of 2000, remembering her first IT job as a quality-checker for Telligentsia, which she takes after a failed bid for an academic job in linguistics. . . .
Cardiff Half Marathon: Runners get engaged near finish line
... " We just got The Bug and we ve actually booked another [half marathon] in two weeks time so we can get the pace that we want, " she said...
Amateur photographer snaps pink grasshopper in Lincoln
... Mr Ward, a keen macro photographer, estimated The Bug was between 15 and 20mm in length, adding: " I didn t think much of it at first until I looked up how rare seeing one actually is...
Pigeon racing: The young fanciers keeping the sport alive
... A year-round commitment, mucking out a pigeon loft is certainly not every child s idea of fun but some young people have caught The Bug from their family...
Dad completes 1,000 days of toy car photos around the UK
... It started as a lockdown project in 2020 but he caught The Bug and it turned into a three-year project capturing images of his son s Hot Wheels miniature cars in locations from Edinburgh Castle to Buckingham Palace...
New superbug-killing antibiotic discovered using AI
... Dr Jonathan Stokes, from McMaster University, describes The Bug as " public enemy number one" as it s " really common" to find cases where it is " resistant to nearly every antibiotic"...
Music festivals where Glastonbury meets Vicar of Dibley
... " The most important thing - the musicMore than 70 Welsh unsigned artists are among the acts at this year s festival hoping to follow in the footsteps of Boy Azooga, BBC 6 Music favourites The Bug Club and Violet Skies and get a record deal after playing Devauden...
Eurovision 2023: Airbnb host tried to increase rent from £465 to over £2,000
... I just love it, I ve got The Bug, " he said...
North West Computer Museum aims to give new life to old consoles
... " The biggest buzz in the world for me would be for a young kid from Leigh to come in and check out an electronics board and then for them to get The Bug and go on to develop their own company, " he said...
New superbug-killing antibiotic discovered using AI
By James GallagherHealth and science correspondent
Scientists have used Artificial Intelligence (AI) to discover a new antibiotic that can kill a Deadly Species of superbug.
The AI helped narrow down thousands of potential chemicals to a handful that could be tested in The Laboratory .
The result was a potent, experimental antibiotic called abaucin, which will need further tests before being used.
The researchers in Canada and the US say AI has The Power to massively accelerate The Discovery of new drugs.
It is the latest example of how the tools of Artificial Intelligence can be a revolutionary force in science and medicine.
Stopping the superbugsAntibiotics kill Bacteria . However, there has been a lack of new drugs for decades and Bacteria are becoming harder to treat, as they evolve resistance to the ones we have.
are estimated to die from infections that resist treatment with antibiotics.
The researchers focused on one of The Most problematic species of Bacteria - which can infect wounds and cause pneumonia.
You may not have heard of it, but it is one of the three superbugs The World Health Organization has identified as.
It is often able to shrug off multiple antibiotics and is a problem in hospitals and care homes, where it can survive on surfaces and medical equipment.
Dr Jonathan Stokes , from Mcmaster University , describes The Bug as " Public Enemy number one" as it's " really common" to find cases where it is " resistant to nearly every antibiotic".
Artificial IntelligenceTo find a new antibiotic, the researchers first had to train the AI. They took thousands of drugs where the precise chemical structure was known, and manually tested them on to see which could slow it down or Kill It .
This information was fed into the AI so it could learn the chemical features of drugs that could attack the problematic bacterium.
The AI was then unleashed on a list of 6,680 compounds whose effectiveness was unknown. The Results - - showed it took the AI an hour and a half to produce a shortlist.
The researchers tested 240 in The Laboratory , and found nine potential antibiotics. One of them was the incredibly potent antibiotic abaucin.
Laboratory experiments showed it could treat infected wounds in mice and was able to kill samples from patients.
However, Dr Stokes told me: " This is when The Work starts. "
The Next step is to perfect the drug in The Laboratory And Then perform clinical trials. He expects The First AI antibiotics could take until 2030 until they are available to be prescribed.
Curiously, this experimental antibiotic had no effect on other species of Bacteria , and works only on.
Many antibiotics kill Bacteria indiscriminately. The researchers believe the precision of abaucin will make it harder for drug-resistance to emerge, and could lead to fewer side-effects.
In principle, the AI could screen tens of millions of potential compounds - Something that would be impractical to do manually.
" AI enhances the rate, and in a Perfect World decreases the cost, with which we can discover these new classes of antibiotic that we desperately need, " Dr Stokes told me.
The researchers tested the principles of AI-aided antibiotic discovery, but have now used that knowledge to Focus On the big nasties. They plan to look at and next.
" This finding further supports the premise that AI can significantly accelerate and expand our search for novel antibiotics, " said Prof James Collins , from the Massachusetts Institute of Technology.
He added: " I'm excited that this work shows that we can use AI to help combat problematic pathogens such as A. baumannii. "
Source of news: bbc.com
