Replication protein A photograph

Replication Protein A

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Classification Protein
Date of Reg.
Date of Upd.
ID1171064
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About Replication Protein A


Replication protein A is the major protein that binds to single-stranded DNA in eukaryotic cells. In vitro, RPA shows a much higher affinity for ssDNA than RNA or double-stranded DNA. During DNA replication, RPA prevents single-stranded DNA from winding back on itself or from forming secondary structures.

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