Overdrive

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anti-inflammatory drug called dexamethasone, it was hailed as a groundbreaking treatment for hospitalized patients seriously ill with Covid-19.

A British study showed, to do that the drug could save Lives - The First International - and it can be used in the NHS immediately.

What is this medicine?

dexamethasone is a Steroid medicine that reduces inflammation by mimicking the anti-inflammatory hormones produced by The Body .

How does it work?

This drug works by dampening The Body 's immune system.

When It Comes to Covid-19, both The Virus itself and The Body 's response in the fight against him, the cause of the inflammation.

But, sometimes the immune system in Overdrive , and it is this reaction that can be Fatal - that's exactly the reaction, which is designed to attack the infection ends up attacking The Body 's own cells.

dexamethasone alleviates this effect.

It is only suitable for people already in hospital and receiving oxygen or mechanical Ventilation - The Most uncomfortable.

The drug does not work on people with lighter symptoms, and for the suppression of your immune system at this point would be helpful.

How effective is it?

According to scientists in the implementation of the studies, one in Three Deaths could be avoided in patients on ventilators.

For patients, which could prevent oxygen, it is that one death in five.

There was no significant advantage for patients who receive respiratory support.

What was the Test?

The results come from The Recovery (Randomised Evaluation of Covid-19-therapy) study, conducted by the University of Oxford.

to test whether already-approved drugs used for other conditions that could also be useful in The Treatment of Covid-19.

Approximately 2,100 patients received 6 mg Daily Dose of dexamethasone in the study.

their progress in comparison with a sample of just over 4,300 patients received no additional treatment.

The Scientists hope that dexamethasone could eventually be used as part of a suite of drugs that could further reduce the deaths even more.

It is now recommended for adults, not including those who are pregnant or breast-feeding.

How widely available the drug is,?

dexamethasone is a low-Cost drug that already exists, and is in good supply.

In the UK The Treatment costs £5. 40 A Day per patient.

It was first in 1957, and was for use in the UK in the early 1960s.

Because it is the drug for so long, from the patent.

that means That many different companies make it, and it is widely available around The World .

This is especially Good News for developing countries and The World health organization this study welcomed the results.

The Department of Health and Social Care says the drug was also added to the government meant a parallel export-list, which bans companies from the purchase of medicines for British patients and sell them for a higher price in Another Country .

What are the other conditions, it will be used?

The drug can help treat various diseases with inflammation or swelling in The Body , or conditions where the immune system goes into Overdrive - for example, severe asthma, the inflammation in the Airways and the lungs, severe allergic reactions or painful, inflamed joints.

dexamethasone is also useful in autoimmune diseases such as rheumatoid arthritis or lupus caused by the immune system mistakenly attacking The Body .

are there any Side Effects ?

Common Side Effects from dexamethasone uses for other conditions such as anxiety, sleep disorders, weight gain and water retention.

Less common Side Effects include diseases of the eyes, blurred vision, and bleeding.

But, coronavirus patients need only a relatively Low Dose should limit Side Effects .

The Chief Medical Officer for England said there would be "no exceeding harms identified when using this dose of dexamethasone in this patient population".

healthcare, immune system, coronavirus pandemic, nhs

Source of news: bbc.com