On Guard
| Use attributes for filter ! | |
| Initial release | France |
|---|---|
| Directors | Philippe de Broca |
| Story by | Paul Féval, père |
| Languages | French, Italian |
| Date of Reg. | |
| Date of Upd. | |
| ID | 1425697 |
About On Guard
Lagardere (Daniel Auteuil), a commoner, meets the Duc de Nevers (Vincent Perez), and the two, both expert swordsmen, develop a close bond. When the duke discovers he has fathered an illegitimate daughter in the countryside, he decides to marry the baby's mother, and brings Lagardere along for the journey. On the day of the wedding, though, the duke is killed by his fiendish cousin, Count Gonzague (Fabrice Luchini). Lagardere escapes with the infant and bides his time until he can exact revenge. …
Dead soldier suffered relentless sexual harassment - Army report
... She phoned one of her friends who was On Guard duty during the night and said please stay on the phone until I fall asleep and just listen and if you hear anything, just ring for help...
Torture, rape, killings: An Indian state's brutal conflict
... " He says they are On Guard round the clock...
Nikki Sanderson says media interest put her in 'constant state of anxiety'
... " " Knowing that you have to be On Guard because there could be someone lurking in a bush to take your photo is not nice, " she said, adding that she remembered seeing people with large cameras and automatically assuming they were paparazzi because she was in a " constant state of anxiety"...
Indian Olympic wrestlers detained as latest protest escalates
... Police in Delhi were also On Guard on Sunday as a group of farmers tried to enter the city to support the wrestlers...
Trump indictment: 'I worry for the times ahead'
... Living in the New York area, we are a bit On Guard but overall I believe these growing pains are necessary for us as a country to affirm who we are - a country where no-one is above the law...
Blue Jean: The lesbian teachers who inspired film about Section 28
... You re constantly On Guard and need to make sure what you re saying doesn t give you away...
Sir Salman Rushdie speaks for the first time about 'colossal attack'
... Remnick asked Sir Salman if he thinks he should have been more On Guard after moving to New York in 2000, having previously lived underground for several years? " Well, I m asking myself that question, and I don t know the answer to it, " he said...
UK plan for national mRNA cancer-vaccine advance
... And because cancer is a complex disease, patients might need several doses to keep the immune system On Guard...
UK plan for national mRNA cancer-vaccine advance
By Michelle RobertsDigital health editor
The UK is embarking on an ambitious plan to accelerate research into mRNA cancer vaccines, with German pharmaceutical company BioNTech.
Following the success of Covid vaccines using the same messenger-ribonucleic-acid technology, scientists now want to conduct more Trials in cancer patients.
And they are hoping to provide this personalised type of treatment to about 10,000 patients by 2030.
Britain is The First nation to sign up to such a partnership.
BioNTech has several international cancer-vaccine Trials in progress but says the UK is ideally placed as it has a great track record and infrastructure for medical research.
Some of the patients in the Trials will have cancer that has already been treated and the vaccine will hopefully prevent it returning.
Others will have advanced, spreading cancers the vaccine might help shrink and control.
Unlike chemotherapy, which attacks lots of different cells as well as the cancer, the mRNA treatment is tailor-made for the individual and presents the immune system with bits of genetic code from the specific cancer so it can attack only the tumour.
This makes it more expensive to produce. BioNTech says it will be affordable for healthcare systems. But much more work is needed to determine whether the cost can be justified for the NHS. Being commercially sensitive, The Details of the partnership between the Government and BioNTech have not been disclosed.
'Wanted poster'BioNTech co-founder Prof Ozlem Tureci told Bbc News : " The UK is a great partner for this endeavour.
" We have seen in the Covid-19 pandemic with The Fast approval of vaccines in the UK that the regulatory authority is exceptional.
" And Then there is the genomic-analysis capabilities. The UK is one of the leading nations in that regard.
" The concept here is to use specific molecular features in individual cancers of patients to encode them into the mRNA vaccines and to train the immune system to attack. "
It was like putting up a bounty or wanted poster, She Said , alerting The Body to be on The Lookout and fight.
And because cancer is a complex disease, patients might need several doses to keep the immune system On Guard .
Health and Social Care Secretary, Steve Barclay said: " Once cancer is detected, we need to ensure The Best possible treatments are available as soon as possible, including for breast, lung and pancreatic cancer.
" BioNTech helped lead The World on a Covid-19 vaccine and they share our commitment to scientific advancement.
" This partnership will mean that, from as early as September, our patients will be among The First to participate in Trials and tests to provide targeted, personalised and precision treatments using transformative new therapies to both treat the existing cancer and help stop it returning. "
Cancer Research UK welcomed The News , but said delays in diagnosis and treatment mean staff are increasingly overstretched and may be unable to find The Time needed to Set Up clinical Trials - if this continued it would mean slower progress towards new treatments.
CRUK spokesman Dr Iain Foulkes said: " mRNA vaccines are one of The Most exciting research developments to come out of the pandemic, and there are strong hints that they could become powerful treatment options for cancer.
" Getting There will require lots more research. "
Source of news: bbc.com
