Dihydrofolate reductase photograph

Dihydrofolate Reductase

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Gene ontology0004146
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ID996553
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About Dihydrofolate Reductase


Dihydrofolate reductase, or DHFR, is an enzyme that reduces dihydrofolic acid to tetrahydrofolic acid, using NADPH as electron donor, which can be converted to the kinds of tetrahydrofolate cofactors used in 1-carbon transfer chemistry. In humans, the DHFR enzyme is encoded by the DHFR gene.

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