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Charles Swanton

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Gender Male
Born Poole
United Kingdom
Doctoral advisor Nic Jones
Field Cancer
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ID1076919
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Charles Swanton Life story


Charles Swanton FRS FMedSci FRCP is British physician scientist specialising in oncology and cancer research.

At least 20,000 annual UK cancer deaths avoidable, says charity

At least 20,000 annual UK cancer deaths avoidable, says charity
Nov 27,2023 8:11 pm

... Prof Charles Swanton, who has been leading that study at the Francis Crick Institute, told BBC News the work could help doctors better predict how a patient s tumour will spread and how to fight it...

Study reveals cancer's ‘infinite' ability to evolve

Study reveals cancer's ‘infinite' ability to evolve
Apr 12,2023 11:30 am

... " That has never been done before at this scale, " said Prof Charles Swanton, from the Francis Crick Institute and University College London...

Air pollution cancer breakthrough will rewrite the rules

Air pollution cancer breakthrough will rewrite the rules
Sep 10,2022 3:11 am

... One of the world s leading experts, Prof Charles Swanton, said the breakthrough marked a " new era"...

The scientists, a 'home-brew' coronavirus test

The scientists, a 'home-brew' coronavirus test
Apr 19,2020 12:16 am

... Charles Swanton s days are busy, but the work is rewarding test...

Drug that prevents half of breast cancers carries on working

Drug that prevents half of breast cancers carries on working
Feb 16,2020 9:07 am

... Prof Charles Swanton, Cancer Research UK s chief clinician, said: Up until now we only knew that tamoxifen has long-lasting benefits, so it s reassuring that this study looking specifically at anastrozole, which has fewer long-term side-effects, gives better protection to women years after they stopped taking the drug...

Skin cancer: Half of people surviving advanced melanoma

Skin cancer: Half of people surviving advanced melanoma
Feb 16,2020 6:40 am

... What do experts think? Prof Charles Swanton, chief clinician at Cancer Research UK, said the progress in melanoma had been incredibly fast ...

'Revolutionary' new class of cancer drugs approved

'Revolutionary' new class of cancer drugs approved
Feb 16,2020 6:30 am

... Prof Charles Swanton, Cancer Research UK s chief clinician, said the drugs were exciting ...

Study reveals cancer's ‘infinite' ability to evolve

Feb 16,2020 6:30 am

By James GallagherHealth and science correspondent

An unprecedented analysis of how cancers grow has revealed an " almost infinite" ability of tumours to evolve and survive, say scientists.

The results of tracking lung cancers for nine years left the research team " surprised" and " in awe" at the formidable force They were up against.

They have concluded we need more Focus On prevention, with a " universal" cure unlikely any Time soon.

Cancer Research said the study showed the importance of early detection.

The study - entitled TracerX - provides The Most in-depth analysis of how cancers evolve and what causes them to spread.

Cancers change and evolve over Time - They are not fixed and immutable. They can become more aggressive: better at evading the immune system And Able to spread around The Body .

A tumour starts as a single, corrupted cell, but becomes a mixture of millions of cells that have all mutated in slightly different ways.

TracerX tracked that diversity and how it changes over Time inside Lung Cancer patients.

" That has never been done before at this scale, " said Prof Charles Swanton , from the Francis Crick Institute and University College London.

More Than 400 People - treated at 13 hospitals in the UK - had biopsies taken from different parts of their Lung Cancer as the disease progressed.

" It has surprised me how adaptable tumours can be, " Prof Swanton told me.

" I don't want to sound too depressing about this, but I Think - Given The Almost Infinite Possibilities in which a tumour can evolve, and the very large number of cells in a late-stage tumour, which could be several hundred billion cells - Then achieving cures in all patients with late-stage disease is a formidable task. "

Prof Swanton said: " I don't Think we're going to be able to come up with universal cures.

" If we want to make the biggest impact we need to Focus On prevention, early detection and early detection of relapse. "

Obesity, smoking, alcohol and poor diet all increase The Risk of some cancers.

Tackling inflammation in The Body is also being seen as a way of preventing cancer. Inflammation is the likely explanation for air pollution causing lung cancers and inflammatory bowel disease increasing The Risk of colon cancer.

The evolutionary analysis has been published across in the journals Nature and Nature Medicine.

The research showed:

The researchers hope the findings could, in The Future , help them predict how a patient's tumour will spread and to tailor treatment.

Dr David Crosby , The Head of prevention and early detection at Cancer Research UK, said: " The exciting results emerging from TracerX improve our understanding that cancer is a disease which evolves as it progresses, meaning that late-stage cancers can become very hard to treat successfully.

" This underscores the crucial importance of further research to help us to detect cancers at the earliest stages of their development or even better, to prevent them from happening at all. "

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Source of news: bbc.com

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