The Trial
Use attributes for filter ! | |
Originally published | April 26, 1925 |
---|---|
Playwright | Franz Kafka |
Original title | Der Process |
Original language | German |
Characters | Josef K. |
Frau Grubach | |
Fräulein Bürstner | |
Uncle Karl | |
Fräulein Montag | |
Genres | Novel |
Philosophical Fiction | |
Dystopian Fiction | |
Absurdist Fiction | |
Paranoid Fiction | |
Liked | |
Courtroom Drama; Crime Drama; Procedural Drama | |
Reviews | · |
Italian | Il processo |
Origin releas | November 29 –; December 13, 2019 |
Produc | Andrea Occhipinti |
Cast | Vittoria Puccini |
Episodes | EpisodesE08 · Episode 8Dec 13, 2019 E07 · Episode 7Dec 13, 2019 E06 · Episode 6Dec 13, 2019 View 5+ more |
Networks | Canale 5 |
Date of Reg. | |
Date of Upd. | |
ID | 909191 |
About The Trial
A group of characters is implicated in the brutal murder of Angelica, a 17 year old girl involved into something bigger than her.
Judge rejects Trump's immunity claim in 2020 election case
... Judge Chutkan had already issued a gag order and denied a request to remove language from the indictment which Mr Trump s lawyers believe could prejudice a jury against him during The Trial...
Lawrence Jones: Ex-tech boss who drugged and raped women jailed
... The Trial heard Jones had left the two women " stupefied and partially conscious" before attacking them...
Donald Trump gag order reinstated in New York civil fraud trial
... Judge Arthur Engoron, who is presiding over The Trial and claims his chambers have been " inundated" with threats, had issued the limited order in October...
Grace Dent 'overwhelmingly sad' after I'm A Celebrity jungle exit
... Following Dent s departure, EastEnders actress Danielle Harold did The Trial instead...
Brianna Ghey: Accused teenager tried to give girl overdose, jury told
... " The Trial heard X had talked about killing another child, known as E, as well as two others but she said child E was the easiest target...
Aretha Franklin's sons are awarded property thanks to a will found in a couch
... Ted, who was his mother s touring guitarist, told The Trial that Franklin would have written a will " conventionally and legally" rather than by " freehand"...
Joanna Parrish murder: French serial killer's ex-wife tried in student cold case
... More than 30 years later, The Trial in the Paris suburb of Nanterre is the first chance for her family to see a semblance of justice...
Brianna Ghey: Teenager had plan to murder schoolgirl, trial hears
... The Trial has previously heard they The pair, who were 15 at the time, cannot be named because of their age and are identified only as girl X, from Warrington, and boy Y, from Leigh, Greater Manchester...
Coronavirus treatment: when are we going to a drug to treat it?
Vaccines have transformed the pandemic, but there is still a huge need for drugs which can treat Covid.
Immunity from vaccines can wane, and access is still a Major Problem around The World . Also, new variants emphasise the possible need for a back-up.
What drugs are available?There are now many drugs that target The Virus or Our Body in different ways:
anti-inflammatory drugs that stop our immune system overreacting with deadly consequencesanti-viral drugs that make it harder for the coronavirus to replicate inside the bodyantibody therapies that mimic Our Own immune system to attack The VirusThese are all needed at Different Stages of the infection. They range from Dirt Cheap to spectacularly expensive, and some are more resilient to new variants than others.
Anti-inflammatory drugsWhen you catch Covid, your body releases a flood of chemicals to warn that you're Under Attack .
This chemical alarm is called inflammation, and is vital for rallying your immune system to boot out Covid.
But if you don't get rid of The Virus quickly, then inflammation can spiral out of control and eventually damage vital organs such as your lungs. It's this excessive inflammation that kills.
An anti-inflammatory steroid that already existed before Covid - - was The First drug proved to save the lives of people with Covid.
It's given to seriously ill patients with breathing troubles - it cuts The Risk of death by a fifth for patients on oxygen, and by a third for those on ventilators.
It is also so cheap that it has become the go-to drug around The World - with everywhere from Brazil to China using it.
Other anti-inflammatory drugs have been shown to work, including the steroid hydrocortisone.
There are more advanced and targeted anti-inflammatory drugs such as. Tocilizumab has been widely used in hospitals in China, India and Australia.
These are also effective, but up to 100 times as expensive as dexamethasone. This has restricted their use - although they are still cheaper than an intensive care bed.
Anti-inflammatories work best later on in the disease, but an asthma drug called budesonide has been shown to help vulnerable people with early Covid symptoms recover more quickly At Home .
Anti-viral drugsAn anti-viral directly targets The Ability of the coronavirus to make copies of itself inside our bodies.
Such a drug keeps levels of The Virus in The Body low, So There is less of it for your immune system to deal with.
- according to its maker, Pfizer, it cuts The Risk of hospitalisation or death by 89% in vulnerable adults - the manufacturer, Merck, estimates it cuts The Risk of hospitalisation or death by about halfBoth Paxlovid and molnupiravir are best taken soon after symptoms appear.
Pfizer expects to make 80 million courses of Paxlovid by The End of 2022 and has said it will allow generic makers in 95 low-income nations to produce and distribute it at cost price.
Merck is allowing Indian generic drug firms to turn out molnupiravir cheaply for 100 low and middle-income countries.
Another anti-viral, is given through a drip and cuts recovery time from Covid.
Antibody TherapyThe third approach is to give people an infusion of Antibodies that can attack The Virus .
These stick to The Surface of the coronavirus and mark it for destruction by The Body 's immune system.
The Body makes its own Antibodies when it is attacked by coronavirus. The Most effective of these have been studied in The Lab , grown and given to patients. This is known as monoclonal antibody Therapy .
These therapies are often reserved for seriously ill patients who are struggling to make their own Antibodies .
reduces the length of hospital stays and The Risk of death reduces The Risk of hospitalisation and death by 79% in high-risk adultsAgain, the earlier the drugs are given the better the chances of success.
Will the drugs work against new variants?Anti-inflammatories should work against all variants because they target Our Own bodies, rather than The Virus itself.
There is more concern about whether monoclonal Antibodies would work with new variants, as they rely On Being a close match for The Virus . If a new variant is heavily mutated then it theoretically makes the drugs weaker.
However, GSK says it has tested its Therapy against the Omicron variant and it remains effective in laboratory studies.
Anti-virals are expected to hold up against the variants seen So Far . None of The Mutations seen in Omicron should affect The Ability of the drugs to work. However, if the drugs are used widely then there is the potential for Drug Resistance to emerge.
What other drugs are available?A Number of drugs have been heralded as potential therapies for Covid - Sometimes with no sign that they actually make any difference.
Ivermectin has been controversially promoted for use in many parts of The World , despite no evidence that it works.
Taking Antibodies from survivors' Blood - known as convalescent plasma Therapy - has been touted, but has not reduced deaths.
There was also speculation that drugs used to treat malaria and HIV might work, but this has come to nothing.
Follow James
What do I need to know about the coronavirus? SOCIAL DISTANCING: FACE MASKS: SCHOOLS: TESTING: View commentsimmune system, coronavirus pandemic, flu, medical research
Source of news: bbc.com