The Trial

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Elisa Granato was one of The Volunteers

The First human trial in Europe, a Corona-Virus has begun vaccine in Oxford.

Two volunteers were injected, The First recruited by More Than 800 people.

Half the Covid-19-vaccine, and half received a control vaccine protects against meningitis, but not coronavirus.

the design of The study does not mean that The Volunteers know which vaccine you get, although the doctors.

Elisa Granato, one of the two who receive the vaccine, told The Bbc : "I'm a scientist, so I wanted to try to support them, the scientific process, where ever I can. "

The vaccine was developed in less than three months by a team at the University of Oxford. Sarah Gilbert, professor of vaccinology at the Jenner Institute, led the pre-clinical research.

"I Personally have a high level of confidence in the vaccination," She Said .

"of course, we have to test it and collect data from people. We have to show that it actually works and keeps people are becoming infected with Corona Virus prior to the use of the vaccine in the General population. "

Prof Gilbert previously said she was working "80 percent sure" of the vaccine, but not to quantify, rather, it is, just say, she is "very optimistic" about the chances.

So how is the vaccine supposed to Work ?

The vaccine consists of a weakened version of a Common Cold virus (known as adenovirus) from chimpanzees, modified so it can grow in the people.

The Oxford team has already a vaccine against Mers, a different type of coronavirus, the same approach - and this has had promising results in clinical trials.

Fergus a vial of vaccine holds developed by the Oxford team, How will you know if it works?

The only way The Team will know whether the Covid-19 vaccine works, by comparing The Number of people infected with the Corona Virus in The Coming months by the two arms of the study.

This could be a problem if cases are falling rapidly, in the UK, because it may not be enough data.

Prof Andrew Pollard , Director of the Oxford Vaccine Group, leading the study, said: "We're chasing The End of the current wave of epidemics. If we don't catch that we will be able to tell whether the vaccine works in The Next couple of months. But we expect that there will be more cases in The Future , because this virus is still not gone. "

The vaccine-researchers are the priority for hiring local health workers in the study, as they are more likely than others to have contact with The Virus .

A larger study, of about 5,000 volunteers will start in The Coming months and have No Age limit.

Older people tend to have a weaker immune response to vaccines. Researchers are evaluating whether you need two doses of the jab.

The Oxford team is also a vaccine trial in Africa, possibly in Kenya, where the transmission rates are always from a lower base.

If the numbers could be a problem, Why Not be aware of volunteers with coronavirus infect?

That would be a quick and safe way to find out whether the vaccine was effective, but it would be ethically questionable, because there are no proven treatments for Covid-19.

But that could be possible in The Future . Prof Pollard said: "If we reach The Point where we have some treatments for the disease, and we could guarantee the safety of The Volunteers , that would be a Very Good way of testing a vaccine. "

- Is it safe?

The study, volunteers will be carefully monitored in The Coming months. You said that some people get a sore arm, headache or fever in The First few days after vaccination.

they are also told that there is a theoretical risk that The Virus could induce a serious reaction to the Corona-Virus that in some of the early Sars-animal-vaccine-trials.

began Work on a vaccine in January

But the Oxford team says that its data can be The Risk for vaccine-production is an advanced disease at a minimum.

scientists there hope that you are million doses in September, and to dramatically scale-up the production that, should the vaccine prove to be effective.

So, who it would be first?

Prof Gilbert said that it is still not finally decided: "It is really going to dictate our task, what is going to happen, we must just try to get a vaccine that works, and enough of it, And Then it will decide for others. "

Prof Pollard added: "We have to ensure that we have enough doses for those in the greatest need, not only in Britain but also in developing countries. "

Another team at Imperial College London, hopes to begin human trials of its Corona-Virus vaccine in June.

The Oxford and Imperial teams have received More Than £40m of government funding.

health Secretary Matt, has Hancock praised both teams and said that Britain will "we throw everything we have" in the development of a vaccine.

the UK's chief medical adviser, Prof Chris Whitty , neither a vaccine nor a drug for the treatment of Covid-19, is likely to be available within The Next Year .

coronavirus pandemic, vaccination, social distancing, university of oxford

Source of news: bbc.com