David Cameron

Three-year-old Madeleine Mccann disappeared from a Portuguese Holiday Apartment in may 2007.

has taken place In the past few years a huge, expensive Police operation in many parts of Europe.

The recent Met Police investigation, which started in 2011 has been the cost of More Than £11m.

In the latest development, Scotland Yard has travelled to Portugal in a camper van.

Madeleine's parents Kate and Gerry Mccann , who said previously The Bbc , you would have to do, "what will it take it to find as long as it takes", the lost her daughter 13 years ago.

On 3. May, Madeleine, the oldest of the three children of Rothley, Leicestershire, went missing from her family's Holiday Apartment at The Ocean Club in Praia da Luz.

their parents had gone to dinner with a group of Friends - later known as the Tapas Seven - to a restaurant, 100 meters from The Apartment .

Later that evening, Kate Mccann went to check on her three children.

Madeleine had disappeared.

the Police were called and about 60 staff and guests at The Complex searched until daybreak for the Little Girl .

Border Police and airport staff have been put on alert, and hundreds of volunteers joined forces to find efforts to find Madeleine, in The Days .

On 12 may, with No Trace of her, the Mccann 's Problem is not found, a statement that They "describe the pain and despair:" you are feeling.

The Portuguese Police say They believe Madeleine was abducted but is Still Alive and in Portugal.

They have a Suspect in mind.

Three Days later, Briton Robert Murat is a Suspect in an official - or "arguido" - Following a search of His Mother 's villa 150 yards from the McCanns' Holiday Apartment .

On 26 may, the Police a description of A Man who disappear in The Night of Madeleine's "bear a child-or an object, which would have as a child"

In June, a Portuguese Police -confesses-in-chief, vital forensic evidence was destroyed, as The Scene was not properly protected.

In July , The British Police send sniffer dogs to help in The Investigation and inspection of the Mccann 's to be carried out in The Apartment and hire car.

Of August it disappeared 100 Days since Madeleine. The investigating officers publicly acknowledge that she might be dead.

Police deny newspaper speculated that Mr and Mrs are the Mccann as suspects, the McCanns start Qual a Libel case against The Portuguese newspaper Tal &. It had claimed that the Police believe the couple killed their daughter.

The McCanns say that They are "deeply hurt" by the allegations.

About a week later, on the 6. September, Portuguese Police interview Kate Mccann for 11 hours as A Witness .

The Next day, detectives a couple "arguidos make".

The Days after that, the McCanns 'return to Rothley, and The Portuguese Police play down reports that DNA evidence with a 100% match to Madeleine was found in her parents' car.

prosecutors rule there is "no new evidence" to justify the Police files re-questioning Gerry and Kate Mccann .

In October, Goncalo Amaral, The Detective responsible for The Investigation , who criticized The British Police in a Portuguese newspaper interview, from the housing removed.

He is replaced by Paulo Rebelo, Deputy national Director of Portuguese Police .

Gerry Mccann released a personal video, speaking in November of his belief that His Family 's disappearance was watched by "a predator" in The Days before his daughter.

On the 20. January, the McCanns release sketches of a Suspect seen Based on a description by a British vacationer of a "creepy man", in the Resort - you can believe in and kidnapped her daughter.

In March, Mr and Mrs Mccann Accept £550,000 Libel , and a front-page apology from the UK's Express Newspapers over allegations They were responsible for Madeleine's death.

In April, Portuguese Police deny leaking details of statements made by the McCanns early in The Investigation , Fly to the UK to sit in the interviews conducted by Leicestershire Police , the so-called " Tapas Seven.

Spanish TV shows quotes, including some of Mrs Mccann , supposedly telling officers that Madeleine had been upset The Night before she disappeared that her mother had come to her when she cried.

On 3. May is a year since The Disappearance , a weeping Mrs Mccann urges people to "pray like crazy" for the Little Girl .

days later, Alipio Ribeiro, The Portuguese Police Chief criticised for his handling of the case.

From July, Portuguese Police say They have submitted their final report on the case, what is the Attorney General the object of careful analysis and consideration of says "".

weeks later, shelf authorities in their investigation and lift the "arguido" status of the McCanns.

The British expat Robert Murat, who is also discounted as a Suspect , accepts a £600,000 Damages settlement over allegations in 11 UK Newspapers that he was involved in The Disappearance of Madeleine.

meanwhile, The Portuguese detective Mr Amaral published a book entitled on the case, The Truth of The Lie , in which he claimed that Madeleine died in her family apartment.

After the publication of Mr Amaral in the book " the McCanns in may, wants to sue him over remarks he made in the media.

On 3. November, launched a one-minute video Message -produced in seven languages, is from The British Child Exploitation and Online Protection Centre, showing new images of how Madeleine might look, More Than two years older.

In March 2010, the McCanns criticise the release of previously unreleased, Portuguese Police files and British Newspapers

The 2,000-page dossier details dozens of possible sightings of Madeleine since her disappearance.

A month later, in April, Gerry Mccann says it is "incredibly frustrating" that Police in Portugal and the UK were actively looking for his daughter "for a very long time".

In November, will write to the couple to sign a record contract, a book about Madeleine ' s disappearance. Start a petition for a full examination of the case by the United Kingdom and Portugal.

The Mccann 's book, Madeleine, will be published in may.

In an open letter, published in the newspaper "Sun", you are calling for Prime Minister David Cameron to launch an independent review of all information in connection with The Disappearance of Madeleine.

The Next day, he writes to the couple and says to you, Home Secretary Theresa May , in the Note to "new action" with the Metropolitan Police .

In September, the McCanns request "core participants" in The First part of the Leveson Inquiry into the phone-hacking scandal.

When you give evidence in November, the couple say that request that you leave, the earlier by press suggestions They were responsible for Madeleine's death.

her lawyer, David Sherborne, describes the McCanns' treatment by The Press as a "national scandal".

In her evidence to the Leveson inquiry in January, Daily Star editor Dawn Neesom said she regrets that The Paper cover of The Disappearance of Madeleine.

Det Ch TÜV Andy Redwood, The Detective leading the UK review of Madeleine's disappearance, says to initiate a broadcast of The Bbc Panorama programme that his team "is looking to be the case".

A computer-generated image of what might look like Madeleine, which is published at the age of nine, not to say A Day before The Portuguese authorities, They are re-opening their investigation.

In may, British detectives reviewing the case say They have identified "A Number of persons of interest".

From July, Scotland Yard announces that it has "new evidence and new witnesses" in the case, and. He says it is investigating 38 "persons of interest".

The Mccann 's £1m Libel action against former Portuguese Police Chief Goncalo Amaral begins in Lisbon in September.

Of October, Scotland Yard detectives say They have identified 41 possible suspects.

A BBC Crimewatch appeal features e-fit images of A Man seen carrying a blond child of three or four, possibly in pyjamas, in Praia da Luz, went missing about the same time, Madeleine.

It also shows a detailed reconstruction of the events of The Night she disappeared.

The Portuguese Police to reopen their investigation - parallel to Scotland Yard 's - citing "new lines of inquiry".

Source of news: bbc.com